Cilician Plains is the last part of the country where malaria has not been totally eradicatedâit was indeed a common disease in the region until up to 1980s, and it's reported that there are still weakened populations of P. vivax in the region. While you will most likely be safe, take usual precautions i.e., apply insect repellents liberally at visits May through October, when mosquitoes are active, and go see a doctor if you happen to perceive the symptoms within two weeks after your visit to the region.
Be careful while driving on the quite desolate motorway between Adana and Osmaniye, as mentioned at "get around" section.
