Aegean Region to the north/northwest has a lot in common with Mediterranean Turkey especially the climate, landscape, and flora, yet has unique aspects that make it a separate region.
Northern Cyprus is a short ferry hop away to the south.
Most travellers intending to get deep into Middle East to the southeast of region cross to Syria from one of the border gates around Antakya.
If the Seljuq sites in Alanya and Antalya aroused your interest, head north to Central Anatolia for a lot more.
Southeastern Anatolia to east is quite an off the beaten path destination and is an altogether different world.
