By plane
By plane
Many major metropolitan areas also have secondary international and regional airports, supporting national, discount and commuter airlines.
By car
By car
In addition to the major interstates listed above, many Midwest cities have secondary interstate service such as outerbelt and by-pass systems.
By train
By train
Most of the Midwest lacks regional passenger rail service, but segments of Amtrak routes may suffice. Chicago, however, is a major Amtrak hub.
By bus
By bus
Greyhound and Megabus offer a variety of routes and connections to guide through the Midwest.