From the north or south, the best access to Clarksville is I-65. There are five exits to Clarksville: Exit 0 Jeffersonville's Court Ave will lead westward towards Clarksville's riverfront, Exit 1 Browns Station Way offers access to Stansifer Ave, Exit 2 Eastern Blvd, Exit 4 Lewis & Clark Pkwy and Exit 5 Veterans Pkwy. From New Albany, Spring St. leads to Browns Station Way, which runs through Clarksville. I-265 has no direct access to Clarksville so motorists from the west I-64 or northeast IN 62 will need to exit to I-65 SOUTH to reach Clarksville.
Commericial air service is offered at Louisville International Airport, ten miles away. Smaller aircraft use Clark County Airport in Sellersburg, five miles away.
There is no Amtrak service to Clarksville.
