From The North
Depending on whichever is closest, take I-75 south, I-275 south, or Southfield Freeway M-39 south. If taking I-75, exit at Southfield Rd. and head east until it terminates at the Detroit river. If taking Southfield Freeway, go until it becomes Southfield Rd. and do the same. When you hit the river, go south on West Jefferson until you are in the heart of downtown Wyandotte.
If I-275 south is closer, take it and exit at Eureka Rd. Go east on Eureka until you hit downtown Wyandotte about 20 minutes.