I-76 / US-224 runs along the North side of Barberton. There are exits for SR-619 and Barber Road, South Cleveland Massilon Road, and SR-21.
SR-21 runs along the West side of Barberton providing Barberton Exits at the I-76 / US-224 interchange and SR-21's intersection with SR-585 and Wooster Road, the latter of which becoming a main road through the city.
