By bus
Buses leave regularly from behind the Luxor Temple, to most major cities. For connections to Aswan and Cairo, the train is recommended, but it is a good alternative to get to Sinai via Hurghada--Sharm el Sheik, or over the Suez canal.
By plane
Luxor International Airport ICAO: LXR is a destination for flights on several European and Middle Eastern routes, as well as the main southern hub for domestic flights within Egypt.
Internal flights duration approx. 1 hr from Cairo to Luxor are maintained by Egyptair (http://www.egyptair.com/) and cost about $120 for a return trip ticket.
Direct charters from Europe London Gatwick, for example are common in the winter high season. From the airport in Luxor, you will probably take a shuttle provided by your hotel. Note that the Airport in Luxor is very small, and getting luggage off the belt is a challenge.
EgyptAir also arranges day trips from Cairo which is an easy way for those who can stand long days to cover the main attractions of Luxor. Taxis are in abundance everywhere for local transportation.
Visitor visas are available on arrival to many foreign nationals, just after you enter the terminal building. 15$ or equivalent, approximately LE 86, most major foreign currencies accepted.
A taxi from the airport into town should cost no more than 50EGP. Do not be fooled by the cartel of taxi drivers outside the doors to the airport. keep walking until you find a taxi driver in his car and then negotiate. Half the people you think are taxi drivers are just touts, so don't waste your time negotiating.