Neu-Isenburg is very well connected and has entries/exits to the Autobahns A3, A5 and A661 plus the federal street B43 shortcut to the airport. In the morning and evening rush hour most Autobahns are congested so plan additional time if you travel to Frankfurt or to the trade fair. There is a direct bus to/from the airport Bus 651 from Airport Terminal 1 that leaves twice per hour and the railway is well connected to Frankfurt main station.
