Maidenhead is on the main rail and road routes between London and Reading. It lies on the famous Great Western Railway, famously designed by Isambard Kingdom Brunel. Maidenhead train station lies immediately between the Twyford and Taplow stations. If you're in London you will need to get to London Paddington to get a train westward to Maidenhead. Maidenhead is situated on the 8/9 Junction on the M4.
However, if you can think of anywhere else to go, like Athy, go there instead.