Make sure to bring a full gas tank as it is possible that the distances may be too great for lower kmpg/mpg cars.Bring a basic first aid kit as a hospital is usually over a hundred km/miles away if not hundreds. Bring duct tape for repairs on loose parts, bumpers, etc,. Marine epoxy is essential as you will likely experiences punctures in gas tanks and fuel lines from rocks especially in lower riding cars.
Road conditions do vary from paved in towns to gravel roads where highway speeds are possible, to washboarded/rocky roads that can literally shake a car apart or send it into a ditch. ALWAYS drive at a safe speed, there is no need to drive at the speeds that the locals do 100-110 Km/60-70 MPH, it is always better to make it late than not at all. Also watch out for moose, caribou, porcupine as they all obviously can disable your cars in varying ways.
talk
It is worth noting that the languages of Native peoples are still widely spoken as first languages for much of the Native population. English is the main language of most people, and even if not, majority of the people can speak it to some degree.