Understand
The Mission District fit in with the locals by just calling it "The Mission" lies to the east of the oldest building in San Francisco, Mission Dolores, though that building is located just within Noe Valley. The area was the site of the Spanish mission that was the kernel of the city San Francisco is today. The mission itself was secularized in the 1820s, and the lands were given to the Native Americans who lived there. Many sold or lost the land in later years.
During the 19th century, the Mission District was physically separated from San Francisco proper, which mostly clustered around the seaport on the San Francisco Bay. The district's area was a pleasant country day trip for San Franciscans, and soon grew into a small village. By the end of the 1800s, the area had been assimilated into the rest of the city.
By the early 20th century, after the 1906 earthquake that destroyed several blue-collar neighborhoods, Irish and Italians relocated to the quickly expanding Mission District. From the 1940s the district gradually became more populated with Mexican/Latin-American immigrants creating a strong counterculture in the arts and politics during the civil rights movement. Following this era, the Mission remained a strongly Chicano and Latin-American neighborhood, but also with a great contingency of African-American, Asian-American and European-American driven by the relatively cheap rents in the neighborhood. In the 1980s and early 1990s, it attracted an influx of new artists, musicians, and other counterculture types.
By the turn of the 21st century, the district experienced an increased gentrification. Expensive restaurants and the construction of "live-work" spaces were moving in to the area, displacing hundreds of residents. However, as the post-Internet boom recedes, the wave of affluence is partly diminishing and the Mission is continuing to be a place for multicultural encounters, where long term residents, immigrants, hipsters and yuppies are living side-by-side.
Bernal Heights, just south of the Mission District, is a cute, eclectic neighborhood that was once very working class, but is becoming quickly gentrified. Sister to the Castro, this neighborhood is very popular with the lesbian community. The main commercial drag of the neighborhood is located along Cortland Avenue.