The primary means of getting to Sutherland is Interstate 80, which runs east-west; US 25 comes into Sutherland from the south. Highway 30, named the Lincoln Highway Scenic Byway, runs east-west. Lincoln is 3.5 hours east on I-80; Cheyenne is 3.5 hours west on I-80; Denver is 3.5 hours west on I-80 and I-76.
North Platte Regional Airport is served by Great Lakes Aviation with connecting flights to Denver International Airport.